The Delta variant raised concern regarding its ability to evade SARS-CoV-2 vaccines.We evaluated a serum neutralizing response of 172 Italian healthcare workers, three months after complete Comirnaty (BNT162b2 mRNA, BioNTech-copyright) vaccination, testing their sera against viral isolates of Alpha, Gamma and Delta variants, including 36 subjects w
Predicting enrollment performance of investigational centers in phase III multi-center clinical trials
Failure to meet subject recruitment targets in clinical trials continues to be a widespread problem with potentially serious scientific, logistical, financial and ethical consequences.On the operational level, enrollment-related issues may be mitigated by careful site selection and by allocating monitoring or training resources proportionally to th
Hypersensitivity pneumonitis in a child (observational data for six years): A clinical case
Background.Hypersensitivity pneumonitis refers to a rare interstitial lung disease that requires differential diagnosis with a large spectrum of nosologies.However, the prevalence of hypersensitivity pneumonitis in the population remains synovex one grass unclear, partly due to low awareness among healthcare professionals of various specialties reg
Accounting conservatism and economic conditions: Evidence from the GIPS and the UK
In this article we analyse whether the level of conservative accounting practice is associated with economic conditions in Greece, Ireland, Portugal, Spain (GIPS) and the UK.For that purpose, we study conditional conservatism surrounding the 2007/08 global financial crisis, using an approach that consists in examining two stages of the kenya tree c